乙醇胺缩合胺化反应合成乙二胺研究进展

Progress in selective synthesis of ethylenediamine via condensation amination of monoethanolamine

乙醇胺(MEA)缩合胺化反应是一种绿色、高效的乙二胺(EDA)催化合成技术。本文综述了MEA缩合胺化反应合成EDA的催化反应过程、缩合胺化催化剂及胺化产物分离纯化技术的最新研究进展和动向,重点探讨了缩合胺化反应机理、反应热力学及动力学、催化剂酸性及孔道结构对反应性能的影响、催化剂失活、胺化产物分离纯化技术等,总结了缩合胺化反应合成EDA工艺过程中存在的技术问题。提出通过制备多级孔道沸石分子筛催化剂实现择形催化与高效扩散之间的协调统一;通过强化分子筛催化剂改性方法研究,实现催化剂表面酸性的精确调控。在择形催化和酸催化的协同作用下,有望从根本上解决缩合胺化反应中存在的技术问题,加快缩合胺化反应工艺技术的工业化应用普及。

Condensation amination of monoethanolamine(MEA)is a green and efficient method in selective synthesis of ethylenediamine(EDA).Progresses and trends in reaction process,catalyst,separation and purification are reviewed in this work.Reaction mechanism,thermodynamics and kinetics,effect of catalysts including acidity,pore properties and deactivation,separation and purification are discussed in detail.Furthermore,the core issues in the industrialization of this reaction are analyzed and it's pointed out that fabrication of hierarchical zeolite with tunable surface acidity is an effective way to overcome the diffusion limitation in selective synthesis of EDA.Via the synergism between shape selective catalysis and acid catalysis,it is expected to overcome the problems and promote the application in selective synthesis of EDA via condensation amination of MEA in industry.