辅助生殖双胎受孕妊娠高血压综合征产妇及新生儿围生期结局分析

Analysis of the outcome of the pregnant women with assisted reproduction twin pregnancy-induced hypertension and newborns during the perinatal period

目的:分析妊娠高血压综合征对辅助生殖双胎受孕产妇及新生儿围生期的结局。方法:2009年1月-2018年12月收治辅助生殖双胎受孕妊娠高血压综合征产妇13例,作为观察组;选取自然双胎受孕妊娠高血压综合征产妇24例,作为对照1组;选取辅助生殖双胎受孕非妊娠高血压综合征产妇63例,作为对照2组。比较三组产妇及新生儿围生期结局。结果:观察组产妇年龄、住院天数均大于对照1组,差异有统计学意义(P<0.05);观察组产妇孕周小于对照2组,住院天数大于对照2组,差异有统计学意义(P<0.05)。观察组新生儿早产率较高,出现新生儿肺炎、黄疸及小于胎龄儿的发生率均高于对照2组,脏器异常发生率高于对照1组,差异均有统计学意义(P<0.05)。结论:辅助生殖双胎妊娠高血压综合征患者容易分娩早产儿,新生儿在娩出后出现并发症发生率较高,需加以重视。

Objective:To analyze the outcome of pregnancy-induced hypertension to the pregnant women with assisted reproduction twin and newborns during the perinatal period.Methods:From January 2009 to December 2018,13 pregnant women with assisted reproduction twin pregnancy-induced hypertension were selected and treated as observation group.24 cases of pregnant women with hypertension syndrome during natural twin pregnancy were selected as control group 1.63 pregnant women of assisted reproduction twins without pregnancy-induced hypertension were selected as control group 2.The perinatal outcomes of maternal and neonatal between the three groups were compared.Results:The maternal age and length of stay in the observation group were all greater than the control group,with the differences were statistically significant(P<0.05).In the observation group,the gestational weeks were smaller than the control group 2,and the length of hospital stay was larger than the control group 2,with the differences were statistically significant(P<0.05).The incidence of neonatal preterm birth,neonatal pneumonia,the incidence of jaundice and small gestational age children in the observation group was significantly higher than the control group 2,and the incidence of organ abnormalities was significantly higher than the control group 1,with the differences were statistically significant(P<0.05).Conclusion:It is easy to give birth to premature infants with assisted reproduction twin pregnancy-induced hypertension,and newborns have a high risk chance of complications after delivery,which should be taken seriously.