参芪扶正汤加减治疗宫颈癌术后化疗患者临床观察

Observation on the Clinical Effect of Shenqi Fuzheng Decoction on Postoperative Chemotherapy Patients of Cervical Cancer

目的系统性评估参芪扶正汤加减对宫颈癌术后化疗患者的临床效果。方法选取2018年11月—2019年11月住院并接受治疗的宫颈癌术后化疗患者60例,入组患者均采用信封法随机分为对照组和试验组。对照组30例,术后应用顺铂化疗方案,试验组30例,在对照组基础上联合参芪扶正汤加减治疗方案,观察2组患者治疗前后KPS评分、不良反应发生率及中医证候积分变化情况。结果经临床治疗,试验组中医证候积分(5.32±1.56)分,KPS评分(73.92±5.36)分,不良反应发生率16.67%;对照组中医证候积分(9.41±1.45)分,KPS评分(65.72±4.33)分,不良反应发生率30.00%,试验组均优于对照组,差异有统计学意义(P<0.05)。结论宫颈癌术后接受顺铂化疗患者联合参芪扶正汤内服治疗可显著减轻化疗药物对患者免疫系统及消化道、肝肾功能的损伤,降低不良反应发生率,改善患者免疫力,提高预后效率,临床效果显著,值得临床推广。

Objective To systematically evaluate the clinical effect of modified Shenqi Fuzheng decoction on patients underwent postoperative chemotherapy for cervical cancer.Methods Sixty patients with postoperative chemotherapy for cervical cancer from November 2018 to November 2019 were selected.All patients were randomly divided into control group and experimental group by envelope method.30 patients in the control group were treated with cisplatin chemotherapy,and 30 patients in the experimental group were treated with Shenqi Fuzheng decoction on the basis of the control group.Results After clinical treatment,in the experimental group,TCM syndrome score was(5.32±1.56),KPS score was(73.92±5.36),and incidence of side effects was 16.67%.In the control group,TCM syndrome score was(9.41±1.45),KPS score was(65.72±4.33),and incidence of side effects was30.00%.The experimental group was superior to the control group,and the significance was statistically significant(P<0.05).Conclusion The cisplatin chemotherapy after cervical cancer combined with Shenqi Fuzheng decoction orally can significantly reduce the damage of chemotherapy drugs to patients’immune system,and is worthy of clinical promotion.