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骨硬化蛋白在慢性肾脏病-矿物质和骨代谢异常中的研究进展 被引量:5

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摘要 慢性肾脏病(chronic kidney disease,CKD)患者由于出现了心血管并发症而伴有高死亡率[1]。慢性肾脏病-矿物质和骨代谢异常(chronic kidney disease-mineral bone disorder,CKDMBD)是慢性肾脏病导致的矿物质和骨代谢异常综合征,常导致心血管风险增加[2]。过去几十年的研究发现高磷血症、血管钙化以及成纤维细胞因子23(fibroblast growth factor,FGF23)升高是导致心血管风险增加的主要三因素[3]。
出处 《中国中西医结合肾病杂志》 2020年第9期832-835,共4页 Chinese Journal of Integrated Traditional and Western Nephrology
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