系统综述阿比多尔用于新型冠状病毒肺炎治疗的临床可行性

Clinical feasibility of arbidol in treatment of COVID-19:a systematic review

阿比多尔具有广谱抗病毒活性,在流感病毒和其他呼吸道病毒感染的预防和治疗方面均有明显的作用,能显著改善患者临床症状和生命体征,最终提高患者生活质量,是应用前景最广泛的抗病毒药物之一。当前,新型冠状病毒肺炎(COVID-19)疫情已全球大流行,对全球人民的生命安全构成重大威胁。阿比多尔因其广谱抗病毒作用,具有巨大的临床应用潜力,被加入到我国抗击疫情的诊疗方案中,并协同其他抗病毒药物为患者带来了良好的治疗效果。本文基于阿比多尔既往抗病毒治疗研究,系统综述阿比多尔用于COVID-19治疗的可行性,以期为临床合理使用提供参考。

Arbidol has a broad-spectrum antiviral activity,which has a significant role in the prevention and treatment of influenza virus and other respiratory viral infections.As one of the most widely used antiviral drugs,it can significantly improve patients’clinical symptoms and vital signs,and ultimately improve the quality of life.Currently,corona virus disease 2019(COVID-19)has become a global pandemic,posing a major threat to the lives of people around the world.Because of its broad spectrum antiviral effect,arbidol has huge potential and has been added to the diagnosis and treatment plan for combating the epidemic in China,and cooperated with other antiviral drug to bring good therapeutic effects to patients.Therefore,based on the previous antiviral treatment of arbidol,the feasibility of arbidol for COVID-19,with a view to providing a reference for rational clinical use were systematically reviewed in this article.