心气虚与冠脉病变及心脏结构相关性研究

Research on the Correlation between Heart Qi Deficiency and Coronary Artery Lesions and Heart Structure

目的研究心气虚与冠脉病变、血运重建、心脏结构是否存在相关性。方法通过收集东直门医院和安贞医院166例病例,冠脉病变数量按单支、双支、三支病变分组,冠脉病变严重程度以轻中重完全闭塞分组,建立EpiDate3.1数据库,通过SPSS 17.0统计软件统计分析,以P<0.05为差异有统计学意义。结果心气虚与冠状动脉病变支数密切相关(P<0.05),与冠脉病变严重程度并无相关(P>0.05),心气虚与血运重建有相关性,与无血运重建组比较,差异有统计学意义(P<0.05),心气虚证的轻中重程度按轻、中、重、完全闭塞分组,血运重建按行PCI(1枚、2枚、3枚及3枚以上支架)、冠脉搭桥分组,显示心气虚证半定量分级与支架植入数目无相关性(P>0.05)。超声心动的分析显示在LVD、IVST、LVEF、E/A方面有改变。结论本研究显示冠心病心气虚证与冠状动脉病支数及血运重建术密切相关,且冠心病心气虚证患者心脏结构相应发生改变。

Objective To study the correlation between heart qi deficiency and coronary artery disease,revascularization and cardiac structure.Methods 166 cases were collected from dongzhimen hospital and anzhen hospital,and the number of coronary artery lesions was divided into groups by single-vessel,double-vessel and triple-vessel lesions.The severity of coronary artery diseases was divided into mild,medium and severe complete occlusion groups.EpiDate3.1 database was established and statistical analysis was conducted with SPSS17.0 statistical software.P<0.05 was considered as statistically significant difference.Results Heart qi deficiency is closely related to the coronary artery lesions(P<0.01),the difference was statistically significant in terms of coronary artery lesions counts(P<0.05),coronary artery disease severity and no correlation(P>0.05),heart qi deficiency and revascularization difference was statistically significant(P<0.05),in the light of heart qi deficiency syndrome according to the light,medium and heavy weight,totally occluded grouping.Revascularization was grouped by PCI(1,2,3 or more stents)and OPCAB,the results showed that there was no correlation between the semi-quantitative grading of heart qi deficiency syndrome and the number of stents(P>0.05).Analysis of echocardiography revealed changes in LVD,IVST,LVEF and E/A.