复发性急性胰腺炎的临床特点研究

Clinical characteristics of recurrent acute pancreatitis

目的探讨复发性胰腺炎的临床特点。方法选取2014年2月至2017年2月四川省人民医院急诊科收治的急性胰腺炎患者266例,其中首发急性胰腺炎患者160例为初发组,复发性急性胰腺炎患106例为复发组。查阅病历收集并比较两组患者的性别、年龄、病因、住院时间、病死率、并发症。结果两组患者性别、年龄、住院时间、病死率比较,差异无统计学意义(P>0.05)。两组患者急性液体积聚、包裹性坏死、胰腺假性囊肿、胸腔积液、器官功能衰竭等并发症发生率比较,差异无统计学意义(P>0.05)。初发组主要病因依次为胆道疾病、高甘油三酯血症、酒精性,复发组依次为高甘油三酯血症、胆道疾病、酒精性。复发组甘油三酯血症显著高于初发组,胆道疾病低于初发组,差异均有统计学意义(P<0.05)。结论对急性胰腺炎患者尽早确定病因且有针对性的治疗,以有效预防急性胰腺炎的复发。

Objective To investigate the clinical characteristics of recurrent pancreatitis( RAP).Methods A total of 266 patients with acute pancreatitis admitted to the emergency department of our hospital from February 2014 to February 2017 were selected.Of them,160 were first-episode acute pancreatitis( initial group) and 106 were recurrent acute pancreatitis( recurrence group).The gender,age,etiology,length of hospital stay,mortality and complications of the two groups were compared.Results There was no significant difference in gender,age,length of stay and mortality between the two groups( P>0. 05).There was no significant difference in the incidence of complications such as acute fluid accumulation,encapsulated necrosis,pancreatic pseudocyst,pleural effusion and organ failure between the two groups( P>0. 05).The main causes of the initial group were hyperlipidemia,biliary tract disease and alcoholism,and the recurrent group was biliary tract disease,hyperlipidemia and alcohol. The incidence of biliary disease in the initial group was significantly higher than that in the recurrence group( P<0. 05),while triglyceridemia in the recurrent group was significantly higher than that in the initial group( P<0. 05).Conclusion For patients with acute pancreatitis,it should find out the definite cause and perform targeted treatment as soon as possible.Thus,it could effectively prevent the recurrence of acute pancreatitis.