健脾益肾法辨证治疗慢性肾脏病5期患者临床疗效及安全性

Clinical Effect of Magnesium Sulfate Combined with Nifedipine in Treatment of Hypertension during Pregnancy

目的观察健脾益肾法辨证治疗在慢性肾脏病5期患者中的应用效果及其应用安全性。方法选取2018年5月至2019年5月辽源市西安区人民医院接收的80例慢性肾脏病患者,采用随机数字表法分为对照组与观察组,各40例。对照组为常规基础疗法,观察组为健脾益肾法辨证治疗。结果治疗后两组肾小球滤过率提高,血尿素氮、血肌酐水平降低,差异有统计学意义(P<0.05),且观察组上述指标改善更明显,差异有统计学意义(P<0.05)。观察组与对照组不良反应的比较,差异有统计学意义(P<0.05)。观察组治疗有效率97.50%,高于对照组的80.00%,差异有统计学意义(P<0.05)。结论对慢性肾脏病5期患者实施健脾益肾法辨证治疗,能够改善患者肾功能,提高治疗效果。

Objective To observe the effect and safety of syndrome differentiation of spleen-invigorating and kidney-invigorating method in patients with chronic extension and stage 5.Methods From May 2018 to May 2019,80 patients with chronic kidney disease received by Liaoyuan City Xi'an District People's Hospital were selected as subjects for clinical analysis and research.The patients were divided into control group and observation group by random number table,with 40 cases each.The control group was the conventional basic therapy,while the observation group was the syndrome differentiation treatment of invigorating spleen and benefiting kidney.Results Results after treatment,glomerular filtration rate was increased,blood urea nitrogen and serum creatinine levels were decreased in the two groups,the difference was statistically significant(P<0.05),and the above indicators in the observation group were improved more significantly,the difference was statistically significant(P<0.05).There was significant difference between the observation group and the control group in adverse reactions(P<0.05).The effective rate of the observation group was 97.50%,higher than 80.00%of the control group,the difference was statistically significant(P<0.05).Conclusion The spleen-invigorating and kidney-enriching syndrome differentiation therapy can improve the renal function,control the occurrence of adverse reactions and improve the therapeutic effect in patients with chronic kidney disease in stage 5.