左心室辅助装置作为晚期心力衰竭终末替代治疗的研究进展

Left Ventricular Assist Device as Destination Therapy in End-stage Heart Failure

心力衰竭已成为一个全球性问题,其发病率和患病率正以惊人的速度增加。尽管规范化的药物治疗和心脏再同步化治疗等器械治疗可缓解部分患者的症状,但仍有大量患者对此疗效不佳。对于这些患者可进行心脏移植治疗,但目前中国心脏移植在临床应用非常有限;而左心室辅助装置为这些患者提供了一种较理想的替代治疗方案,现就左心室辅助装置作为晚期心力衰竭患者终末替代治疗的研究进展进行综述。

Heart failure has become a global problem,and its incidence and prevalence are increasing at an alarming rate.Some heart failure patients respond poorly to standard guideline medical therapy and devices such as cardiac resynchronization therapy.For these patients,heart transplantation can be performed,but the current clinical application of heart transplantation in China is very limited.Left ventricular assist device provides as an ideal destination therapy for these patients.This review makes a summary on recent progress of left ventricular assist device as destination therapy.