焦虑与非酒精性脂肪性肝病的关系

Association between anxiety and nonalcoholic fatty liver disease

近年来,随着生活方式的迅速改变,非酒精性脂肪性肝病(NAFLD)的患病率逐年递增并逐渐成为慢性肝病的主要病因之一。因生物-心理-社会医学模式的发展,心理疾病对躯体疾病的影响开始受到学者的关注。目前,研究显示焦虑作为最常见的精神障碍之一,其可能与NAFLD的发生发展有关。介绍了焦虑与NAFLD的研究现况以及双方共有的影响因素,并对焦虑致NAFLD的可能病理生理机制进行推测,期望为两者联系的进一步研究奠定基础,并为NAFLD的治疗提出新的方向。

With the rapid change in lifestyle in recent years,the prevalence rate of nonalcoholic fatty liver disease(NAFLD)is increasing year by year and it has gradually become one of the major causes of chronic liver diseases.With the development of the bio-psycho-social medical model,the influence of psychological diseases on physical diseases has attracted the attention of scholars.At present,evidence has shown that anxiety,as one of the most common type of mental disorders,may be associated with the development of NAFLD.This article introduces the current status of research on anxiety and NAFLD and their common influencing factors and predicts the possible pathophysiological mechanism of NAFLD caused by anxiety,so as to lay a foundation for further research on the association between anxiety and NAFLD and provide new directions for the treatment of NAFLD.