血乳酸水平在评估肝衰竭患者预后中的应用

Application of blood lactate level in evaluating the prognosis of liver failure patients

肝衰竭时因乳酸代谢障碍使机体乳酸水平升高,近年来研究血乳酸对肝衰竭的预后具有较高的预测价值。结合近年来的研究发现,介绍LiFe评分预测模型,就血乳酸水平在肝衰竭患者中临床应用的国内外进展进行综述。认为高乳酸水平是肝衰竭患者不良预后的独立危险因素,提出乳酸可作为评估肝衰竭严重程度及预后的重要指标,并能进一步优化相关肝病预后评分系统。

As lactate is elevated due to lactate metabolic disorder in liver failure,recent studies have shown that blood lactate has a high value in predicting the prognosis of liver failure.With reference to the research findings in recent years,this article introduces the prediction model of LiFe score and reviews the advances in the clinical application of blood lactate level in patients with liver failure in China and foreign countries.It is believed that a high lactate level is an independent risk factor for poor prognosis of liver failure patients,and it is proposed that lactate can be used as an important indicator to evaluate the severity and prognosis of liver failure and further optimize the scoring system for the prognosis of related liver diseases.