性病相关门诊女性就诊者生殖道沙眼衣原体感染危险因素分析

Risk factors of urogenital infection with Chlamydia trachomatis among female attendees at sexually transmitted disease clinics

目的了解深圳市性病相关门诊女性就诊者生殖道沙眼衣原体(Chlamydia trachomatis,CT)感染现状及危险因素,为开展相关干预工作提供科学依据。方法招募2018年4月15日至5月16日深圳市22家医疗机构的5742名女性就诊者作为研究对象,开展问卷调查,同时采集尿液样本进行CT和淋球菌检测。结果共调查5742名女性就诊者,生殖道CT阳性率为8.3%(474例),淋球菌感染阳性率0.8%(47例)。多因素Logistic回归分析显示,年龄18~24岁(aOR=2.08,95%CI:1.34~3.25)、25~30岁(aOR=1.85,95%CI:1.25~2.73)、单身(包括未婚、离异及丧偶)(aOR=1.84,95%CI:1.40~2.42)、初中及以下文化程度(aOR=1.58,95%CI:1.17~2.15)、对CT感染不了解(aOR=1.76,95%CI:1.22~2.54)、淋球菌感染阳性(aOR=7.37,95%CI:3.73~14.56)为女性就诊者CT感染的危险因素。结论深圳市女性就诊者的CT感染率普遍较高,且与部分社会人口学因素相关。18~30岁、单身、文化程度偏低、对CT认知偏少以及合并淋球菌感染是深圳市性病相关门诊女性就诊者CT感染的危险因素。

Objective To understand the prevalence of urogenital Chlamydia trachomatis(CT)infection and the risk factors among female attendees at sexually transmitted disease clinics in Shenzhen,so as to provide evidence for developing intervention strategies.Methods A total of 5742 female attendees in 22 participating clinics in Shenzhen were recruited during April 15th and May 16th,2018.They were interviewed by a questionnaire and invited for providing urine samples for CT and Neisseria gonorrhoea(NG)tests.Results Among 5742 female attendees,the positive rates of CT and NG infection were 8.3%(474 cases)and 0.8%(47 cases),respectively.Multivariate Logistic analysis showed that risk factors associated with CT infection included age of 18-24(aOR=2.08,95%CI:1.34-3.25),age of 25-30(aOR=1.85,95%CI:1.25-2.73),single(including unmarried,divorced and widowed)status(aOR=1.84,95%CI:1.40-2.42),middle school or lower education(aOR=1.58,95%CI:1.17-2.15),no awareness of CT(aOR=1.76,95%CI:1.22-2.54),NG infection(aOR=7.37,95%CI:3.73-14.56).Conclusions The female attendees in Shenzhen have a substantial prevalence of CT infection,which is associated with sociodemographic factors.Age of 18-30,single,low education,little knowledge of CT,and co-infection with NG are the risk factors for CT infection of female attendees at sexually transmitted disease clinics in Shenzhen.