摘要
高危人群中性传播感染(STI)的发病率逐年上升。鉴于HIV暴露前后预防的成功经验,化学预防STI传播是安全、有效的防治手段。在男男性行为人群中开展的研究结果显示,无论是暴露前还是暴露后,多西环素均能有效降低STI发病率。本文通过对STI化学预防研究进展进行综述,为化学预防的实施提供科学依据。
The incidence of sexually transmitted infections(STI)in high-risk population is accelerating in the recent years.Considering the success in the HIV pre-exposure prophylaxis(Prep)or post-exposure prophylaxis(Pep),the chemoprophylaxis is a safe and effective method to control the prevalence of STI.Based on the results in men who have sex with men(MSM),the doxycycline can reduce the incidence of STI in Prep or Pep users.The current researches on the chemoprophylaxis in STI are reviewed in this article,so as to promote some effective suggestions for the future researches in chemoprophylaxis.
作者
史灵恩
傅更锋
Shi Ling'en;Fu Gengfeng(Institute for STD and AIDS Control and Prevention,Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210009,China)
出处
《国际流行病学传染病学杂志》
CAS
2020年第5期448-452,共5页
International Journal of Epidemiology and Infectious Disease
关键词
性传播疾病
化学预防
高危人群
多西环素
Sexually transmitted diseases
Chemoprevention
High-risk population
Doxycycline