中西医结合治疗慢性阻塞性肺疾病急性加重期临床观察

Clinical observation of integrated therapy of traditional Chinese and western medicine on acute exacerbation of chronic obstructive pulmonary disease

目的:观察中西医结合治疗慢阻肺急性加重期患者的临床疗效。方法:选取慢阻肺急性加重期患者76例,随机分成两组各38例,对照组给予抗感染、化痰、扩张气道、抗炎解痉及止咳平喘等基础治疗;治疗组在对照组的基础上给予门氏定喘汤加减治疗,治疗两周后比较两组患者的治疗效果及治疗后CAT评分情况。结果:治疗组总有效率92.1%,明显高于对照组68.4%,且差异有统计学意义(P﹤0.01);治疗后治疗组的CAT评分明显低于对照组,并且差异有统计学意义(P﹤0.01)。结论:中西医结合治疗慢阻肺急性加重期患者的总有效率明显优于单纯西医治疗,能够明显改善患者CAT评分,提高患者的生活质量。

Objective:To observe the clinical effect of integrated therapy of traditional Chinese and western medicine on acute exacerbation of chronic obstructive pulmonary disease.Methods:76 cases of selected patients with acute exacerbation of chronic obstructive pulmonary disease were randomly divided into two groups,38 cases in each group.The control group was treated by basic therapy such as anti-infection,eliminating phlegm,dilating airway,antiinflammatory and spasmolysis and relieving cough and asthma,etc.while the treatment group was treated with modified Men's Dingchuan decoction on the basis of control group.After two weeks of treatment,the curative effect and CAT score after treatment were compared between two groups.Results:The total effective rate of treatment group was 92.1%,which was significantly higher than 68.4%of control group,and the difference was statistically significant(P﹤0.01).After treatment,CAT score of treatment group was significantly lower than that of control group,and the difference was statistically significant(P﹤0.01).Conclusion:In treatment of acute exacerbation of chronic obstructive pulmonary disease,the total effective rate of integrated therapy of traditional Chinese and western medicine is significantly higher than that of simple western medicine.In addition,integrated therapy of traditional Chinese and western medicine can significantly improve CAT score of patients,enhance the quality of life of patients with acute exacerbation of chronic obstructive pulmonary disease,and reduce the economic burden of society and family.