活血逐瘀汤联合阿维A治疗寻常型银屑病疗效的随机对照试验

A randomized controlled trial of treating psoriasis vulgaris with the Huoxue Zhuyu decoction plus Acitretin

目的:评价活血逐瘀汤联合阿维A治疗寻常型银屑病血瘀证患者的疗效。方法:采用随机数字表法将我院60例寻常型银屑病血瘀证患者分为观察组与对照组,每组各30例,观察组采用活血逐瘀汤联合阿维A口服治疗,对照组采用阿维A口服治疗。两组疗程均为一个月,连续治疗2个疗程。将治疗前与治疗后的银屑病皮损面积严重指数(Psoriasis Area and Severity Index,PASI)积分、临床疗效以及不良反应进行评估。结果:治疗后观察组和对照组的PASI积分均显著降低(P<0.05),疗效显著(P<0.05)。观察组较对照组的PASI积分显著降低(P<0.05),疗效更好(P<0.05)。结论:活血逐瘀汤联合阿维A比单纯选用阿维A治疗寻常型银屑病血瘀证患者有着更好的疗效、更高的安全性。

Objective:To evaluate the efficacy of the Huoxue Zhuyu decoction(活血逐瘀汤)plus Acitretin on blood stasis syndrome of psoriasis vulgaris.Methods:60 cases were divided into the observation group and control group according to the random number table method,30 cases in each group.The observation group was treated with the Huoxue Zhuyu decoction plus Acitretin oral treatment,and the control group was treated with Acitretin orally.Results:After treatment,the PASI scores in the observation group and the control group were significantly reduced(P<0.05).The PASI score in the observation group was significantly lower than that in the control group(P<0.05).Conclusion:The Huoxue Zhuyu decoction plus Acitretin has better curative effect and higher safety than Acitretin alone on blood stasis syndrome of psoriasis vulgaris.