阿托伐他汀钙片治疗冠心病的总有效率及不良反应发生情况观察

Observation Total Effective Rate and Adverse Reactions of Atorvastatin Calcium Tablets in the Treatment of Coronary Heart Disease

目的研究分析阿托伐他汀钙片治疗冠心病的总有效率及不良反应发生情况。方法在2018年5月至2019年11月到我院就诊治疗的冠心病患者中,选取92例作为本次的研究对象,分为治疗A组和治疗B组,各46例,分别采用常规治疗+辛伐他汀片和常规治疗+阿托伐他汀钙片。对比两组患者的血脂和心肌酶指标水平、治疗总有效率和不良反应发生情况。结果治疗后,治疗B组的血脂和心肌酶指标均得到了比治疗A组稍好一些的改善(P<0.05);治疗总有效率高于治疗A组(P<0.05),且不良反应发生率比治疗A组低(P<0.05)。结论冠心病患者选择阿托伐他汀钙片治疗比辛伐他汀片疗效更好些,并且能有效减少不良反应的发生,具有较高的安全性。

Objective To study the total effective rate and adverse reactions of atorvastatin calcium tablets in the treatment of coronary heart disease.Methods From May 2018 to November 2019,92 patients with coronary heart disease were selected as the study object.The patients were divided into treatment group A and treatment group B,46 cases each.They were treated with conventional therapy+simvastatin tablet and conventional therapy+atorvastatin calcium tablet respectively.The levels of blood lipid and myocardial enzyme,the total effective rate and adverse reactions were compared between the two groups.Results After treatment,the indexes of blood lipid and myocardial enzyme in group B were slightly better than that in group A(P<0.05).The total effective rate was higher than that in group A(P<0.05),and the incidence of adverse reactions was lower than that in group A(P<0.05).Conclusion Compared with simvastatin,atorvastatin calcium tablets is more effective in the treatment of coronary heart disease,and it can effectively reduce the incidence of adverse reactions,and has a higher safety.