如东地区46例类风湿性关节炎患者四项血清学指标检测结果分析

Analysis of the results of four serological indexes in 46 patients with rheumatoid arthritis in Rudong area

目的对本地区46例类风湿性关节炎(RA)患者四项血清学指标类风湿因子(RF)、红细胞沉降率(ESR)、C反应蛋白(CRP)、抗环瓜氨酸肽抗体(Anti-CCP)的测定结果进行统计、分析与探讨。方法本院收治的RA患者46例以及非RA患者59例,测定其四项血清学指标水平,另以40例年龄相当的健康体检者作为对照。结果RA组四项指标均高于对照组,差异具有统计学意义(P<0.05),RA组和非RA组比较,RF、ESR及Anti-CCP具有统计学意义。结论四项指标检测在RA患者中均具有重要的临床价值,若联合检测,可有效提高RA诊断的准确性,减少漏诊误诊。

Objective To analyze the determination results of 46 patients with rheumatoid arthritis(RA)with four serologic indexes such as rheumatoid factor(RF),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)and anticyclic citrullate peptide antibody(Anti-CCP).And exploration.Methods 46 cases of RA patients and 59 cases of non-RA patients were admitted to the hospital.Four levels of serological indicators were determined,and another 40 cases of healthy physical examination were compared.Results The four indexes of RA group were higher than those of control group,and the difference was statistically significant(P<0.05)Compared with non-RA groups,RF,ESR,and Anti-CCP were statistically significant.Conclusion All four indicators have important clinical value in RA patients.If combined,they can effectively improve the accuracy of RA diagnosis and reduce the misdiagnosis.