妊娠期青光眼的药物治疗

Medical treatment of glaucoma in pregnancy

近年来高龄孕妇逐渐增多,对妊娠期女性青光眼的治疗是眼科医师越来越多面临的棘手问题,对这类青光眼患者的药物治疗需要兼顾对母亲妊娠期青光眼视神经损伤进展的有效控制和避免药物对胎儿造成的可能伤害。目前临床上大多数青光眼妊娠期药物使用的经验来自小样本的病例报告或动物实验。虽然妊娠期使用抗青光眼药物对胎儿安全性方面的循证依据不足,如果医生谨慎选择药物种类和改良用药方式,可以尽可能地使青光眼患者和胎儿安全渡过妊娠期。

In recent years,more women are conceiving at older ages and the treatment of glaucoma in pregnancy is an unique challenge faced by more and more glaucoma specialists.The treatment needs consideration of balancing the effective control of the progress of glaucoma to the mother as against the potential harm to the fetus.Most of the available researches of glaucoma medication in pregnancy were based on individual case reports or animal experiments.Although at present there is no strong evidence to verify that anti-glaucoma drug is safe for the fetus,if we carefully select appropriate anti-glaucoma drugs and pay attention to the drug administration method,we can help the glaucoma patients and the fetus pass the pregnancy as safely as possible.