rtPA静脉溶栓治疗急性脑梗死临床效果分析

Clinical Effect Analysis of rtPA Intravenous Thrombolysis in the Treatment of Acute Cerebral Infarction

目的探究rtPA静脉溶栓治疗急性脑梗死临床效果。方法选择该院2018年1月—2019年8月间治疗的57例急性脑梗死患者为研究对象,基于自主原则将其分为对照组(28例)和观察组(29例)。对照组予口服阿司匹林治疗,观察组则实施rtPA静脉溶栓治疗,对比两组治疗前后临床指标及效果。结果两组治疗前CSS评分及Barthel指数对比差异无统计学意义(P>0.05)。治疗后观察组CSS评分(8.10±0.36)分、Barthel指数(84.72±13.09)分明显优于对照组(16.74±1.21)分、(60.31±11.26)分,差异有统计学意义(t=128.955、10.045,P<0.05);观察组治疗总有效率(96.55%)也明显高于对照组(71.43%)(χ2=4.175,P<0.05)。结论实施rtPA静脉溶栓治疗急性脑梗死相比于常规治疗更为理想,能进一步降低患者神经损伤程度,提高治疗效果和患者生活质量。

Objective To explore the clinical effect of rtPA intravenous thrombolysis in the treatment of acute cerebral infarction.Methods The 57 patients with acute cerebral infarction treated in this hospital from January 2018 to August 2019 were selected as the research objects,and they were divided into a control group(28 cases)and an observation group(29 cases)based on the principle of autonomy.The control group was treated with oral aspirin,and the observation group was treated with rtPA intravenous thrombolysis.The clinical indicators and effects of the two groups were compared before and after treatment.Results There was no statistically significant difference in CSS score and Barthel index between the two groups before treatment(P>0.05).After treatment,the observation group's CSS(8.10±0.36)points and Barthel index(84.72±13.09)points were significantly better than the control group’s(16.74±1.21)points and(60.31±11.26)points,the difference was statistically significant(t=128.955,10.045,P<0.05);the total effective rate of treatment in the observation group(96.55%)was also significantly higher than that in the control group(71.43%)(χ2=4.175,P<0.05).Conclusion The implementation of rtPA intravenous thrombolysis for acute cerebral infarction is more ideal than conventional treatment,which can further reduce the degree of nerve damage in patients and improve the treatment effect and quality of life of patients.