舒利迭吸入治疗老年慢阻肺的应用及疗效研究

Seretide Inhalation in the Treatment of Chronic Obstructive Pulmonary Disease in the Elderly

目的探讨舒利迭吸入治疗老年慢阻肺的应用及疗效。方法选取2015年6月—2019年12月该院收治的45例老年慢阻肺患者为研究对象,以随机数字表分为两组。常规药物治疗组进行常规药物治疗,常规药物联合舒利迭吸入治疗组进行常规药物联合舒利迭吸入治疗。分析比较两组效果;咳痰控制时间、咳嗽消失时间、住院时间;用药前后患者肺功能指标和生活质量评分;不良反应。结果常规药物联合舒利迭吸入治疗组用药效果100.00%高于69.57%(χ2=7.843,P<0.05)。用药后常规药物联合舒利迭吸入治疗组肺功能指标和生活质量评分优于常规药物治疗组(P<0.05)。常规药物联合舒利迭吸入治疗组咳痰控制时间、咳嗽消失时间、住院时间(6.02±0.41)、(6.45±1.21)、(10.12±1.05)d优于常规药物治疗组(t=5.216、6.535、5.201,P<0.05);常规药物联合舒利迭吸入治疗组不良反应有1例,发生率4.35%,常规药物治疗组不良反应总出现率有3例,发生率13.64%,两组不良反应发生率差异无统计学意义(χ2=1.034,P>0.05)。结论老年慢阻肺患者行常规药物联合舒利迭吸入治疗效果确切,可改善患者的症状和肺功能,改善其生活质量,且安全性高,无明显不良反应。

Objective To explore the application and efficacy of seretide inhalation in the treatment of chronic obstructive pulmonary disease in the elderly.Methods A random number table of 45 elderly patients with chronic obstructive pulmonary disease admitted in the hospital from June 2015 to December 2019 was collected.The conventional medication group received conventional medication,and the conventional medication combined with seretide inhalation therapy group received conventional medication combined with seretide inhalation therapy.Analyze and compare the effects of the two groups;sputum control time,cough disappearance time,hospital stay;lung function indexes and quality of life scores;adverse reactions of patients before and after medication.Results The effect of conventional medicine combined with seretide inhalation treatment group was 100.00%higher than 69.57%(χ2=7.843,P<0.05).After medication,the pulmonary function index and quality of life score of the conventional drug combined with seretide inhalation treatment group were better than those of the conventional drug treatment group(P<0.05).The conventional medicine combined with seretide inhalation treatment group has better sputum control time,cough disappearance time,hospitalization time(6.02±0.41)d,(6.45±1.21)d,(10.12±1.05)d than the conventional drug treatment group(t=5.216,6.535,5.201,P<0.05);There was 1 case in the conventional drug combined with seretide inhalation treatment group,with an incidence rate of 4.35%,the total incidence of adverse reactions in the conventional drug treatment group was yes 3 cases,the incidence was 13.64%.There were no statisticall significant difference in adverse reactions of the two groups(χ2=1.034,P>0.05).Conclusion Conventional drugs combined with seretide inhalation treatment in elderly patients with COPD has a definite effect, which can improve the symptoms and lung function of the patients, improve their quality of life, and has high safety and no obvious adverse reactions.