玻璃体腔注射康柏西普治疗湿性老年性黄斑变性的临床研究

Clinical Study of Intravitreal Injection of Conbercept in Treatment of Wet Age-related MacuLar Degeneration

目的探讨玻璃体腔注射康柏西普治疗湿性老年性黄斑变性的临床效果。方法选取2016年11月至2017年11月来我院就诊的湿性老年性黄斑变性患的110例为研究对象。按照随机数表法均分为观察组(n=55)和对照组(n=55)。将玻璃体腔注射曲安奈德应用对照组患者中,而观察组应用玻璃体腔注射康柏西普治疗,对比两组治疗前后差异。结果两组治疗前裸眼视力、黄斑中心凹视网膜厚度对比差异无统计学意义(P>0.05),治疗后两组裸眼视力有显著差异,有统计学意义(P<0.05)。结论采用玻璃体腔注射康柏西普对湿性老年性黄斑变性患者实施治疗时,对裸眼视力可取得显著的临床治疗效果,降低黄斑中心视网膜厚度,治疗过程中即可提高患者视力水平,具有十分重要的临床价值和意义,值得推广应用。

Objective to investigate clinical effect of intravitreal injection of conbercept in treatment of wet age-related macular degeneration.Methods choose 110 cases wet age-related macular degeneration patients in our hospital from November 2016 to November 2017 as research objects.According to random number table method,divide them into observation group(n=55)and control group(n=55).Control group was treated with intravitreal injection of triamcinolone acetonide,while observation group with vitreous injection of conbercept.Compare ifference before and after treatment between two groups.Results before treatment,naked eye vision and macular foveal retinal thickness showed no statistically significant difference between two groups(P>0.05).After treatment,naked eye vision difference was statistically significant between two groups(P<0.05).Conclusion intravitreal injection of conbercept can achieve significant clinical effect in treatment of patients with wet age-related macular degeneration for naked eyesight,reduce thickness of macula central retina,improve visual acuity of patients during treatment process,with important clinical value and significance,which is worthy of promotion and application.