摘要
纤维化疾病是现代人类健康的一大威胁,减缓甚至阻断纤维化疾病进展具有重大临床意义。在西医缺乏有效方法的当下,中医药抗纤维化的疗效优势日益凸显。综述苦杏仁苷单体及含有苦杏仁苷复方成分群抗纤维化作用机制研究进展,希望推进苦杏仁苷抗纤维化作用机制研究,对苦杏仁苷临床应用、新药研发有重要意义。
Fibrotic diseases are a major threat to modern human health,and it is of great clinical significance to slow or even block the progression of fibrotic diseases.In the absence of effective methods in Western medicine,the therapeutic advantages of traditional Chinese medicine against fibrosis have become increasingly prominent.In this paper,the research progress of anti-fibrotic mechanism of amygdalin monomer and compound component containing amygdalin was reviewed.It is hoped that the mechanism of anti-fibrosis of amygdalin is promoted,which is of great significance for the development and clinical application of amygdalin.
作者
赵鑫
吕文良
李娟梅
倪瑶
刘俞彤
曹正民
ZHAO Xin;LYU Wenliang;LI Juanmei;NI Yao;LIU Yutong;CAO Zhengmin(Department of Infectious Diseases,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)
出处
《中华中医药学刊》
CAS
北大核心
2020年第10期109-112,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家重点研发计划“中医药现代化研究”专项(2018YFC1705700)
京津冀中医国家临床重点专科肝病协同病房项目(GZY-GCS-2017-60)。
关键词
苦杏仁苷
肝纤维化
肺纤维化
肾纤维化
作用机制
amygdalin
liver fibrosis
lung fibrosis
kidney fibrosis
mechanism of action