“易阳通元”干预痤疮湿热体质提高生活质量临床研究

Clinical Study on Application of Tonifying Yang to Dredge Vital-Qi Principle in Intervention of Damp-heat Constitution of Acne Patients to Improve TheirQuality of Life

目的观察“易阳通元”对痤疮患者湿热体质及生活质量的影响。方法筛选湿热体质痤疮患者60例,分为治疗组与对照组。①治疗组在“易阳通元”法则指导下,采用艾灸大椎、神阙,3次/周,20~30 min/次·穴,配合桂附萸和汤中药方剂,1剂/d,水煎煮,取药汁,200 mL/次,饭后温服,2次/d;对照组给予西药0.05%维A酸软膏外用,每晚用温水清洁皮肤后涂药1次。两组治疗时间均为3个月。治疗前后分别使用湿热体质亚量表测量两组的转化积分。②生活质量判定采用世界卫生组织生活质量简表(WHOQOL-BREF)中文版。由心理、生理、社会关系、环境4个领域共24个问题及总体健康感觉的两个问题组成,共26个问题,得分越高,表示生活质量水平越高。问卷采用定式问卷,附有统一指导语和填表方法说明。问卷经调查员向被调查对象按指导语说明后,现场由被调查人员自评,当场回收问卷。结果①治疗后,治疗组痤疮患者湿热体质亚量表转化积分较前明显下降,治疗前后的差值高于对照组(P<0.05),对照组的转化积分与治疗前相比差异无统计学意义(P>0.05)。②治疗后治疗组WHOQOL-BREF评分较前明显增加(P<0.05);对照组治疗组前后WHOQOL-BREF评分差异无统计学意义(P>0.05)。治疗前后两组WHOQOL-BREF评分比较,治疗组高于对照组(P<0.05)。结论“易阳通元”可明显纠正痤疮患者湿热体质,并提高其生活质量。

Objective To observe the effect of tonifying Yang to dredge vital-Qi principle on the damp-heat constitution and quality of life of acne patients.Methods Sixty cases of acne with damp-heat constitution were divided into treatment group and control group.①Under the guidance of tonifying Yang to dredge vital-Qi principle,the treatment group used moxibustion on Dazhui(DU14)and Shenque(RN8),three times a week,20-30 minutesfor each point,combined with GuifuYuhe Decoction,one dose of a day and twice a day.The control group was given western medicine 0.05%tretinoin ointment for external use,and the skin was cleaned with warm water every night and then applied once.The time of administration was 3 months in both groups.Before and after treatment,the transformation scores of the two groups were measured with the sub scale of damp-heat constitution.②The Chinese version of WHO quality of life brief table(WHOQOL-BREF)was used to determine the quality of life.It is composed of 24 questions in four fields including psychology,physiology,social relations and environment and two questions of overall health feeling.There are 26 questions in total.The higher the score,the higher the quality of life.The questionnaire uses the fixed form questionnaire,with unified guidance words and instructions for filling in the form.After the questionnaire was explained by the investigator to the respondents according to the guidance words,the respondents would make self-assessment on the spot and collected the questionnaire on the spot.Results①After treatment,the score of transformation of damp-heat constitution subscale of acne patients in the treatment group was significantly lower than that before,and the differencewas higher than that in the control group(P<0.05).There was no significant difference between the score of transformation in the control groupbefore and after treatment(P>0.05).②After treatment,the WHO-QOL-BREF score in the treatment group was significantly higher than that before(P<0.05).There was no significant difference in the WHOQOL-BREF score before and after treatment in the control group(P>0.05).After treatment,the WHOQOL-BREF score of the treatment group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion The tonifying Yang to dredge vital-Qimoxibustion can obviously correct the damp-heat constitution of acne patients and improve their quality of life.