慢性阻塞性肺疾病重叠阻塞性睡眠呼吸暂停的诊治

Diagnosis and treatment of chronic obstructive pulmonary disease overlapping obstructive sleep apnea

慢性阻塞性肺疾病(COPD)是呼吸系统常见病,其夜间的病情变化对治疗和预后也有明显影响,尤其当合并睡眠呼吸紊乱如阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)时。近年来的研究表明,不同程度的COPD合并不同程度的OSA对病情影响不同,因此需分层进行治疗。文章将对COPD重叠OSA的诊治策略进行阐述。

Chronic obstructive pulmonary disease(COPD)is characterized as chronic cough and dyspnea.It can coexist with obstructive sleep apnea(OSA),named as overlap syndrome,and manifest lower oxygen saturation during sleep.It has been reported that nocturnal symptoms and hypoxemia are related to the poor prognosis of overlap syndrome.Considering that the severity of OSA has different effect on COPD and vice versa,the management for overlap syndrome need to be carefully stratified and is summarized as follows.