中国人群血型与肝癌发病风险的关系的Meta分析

Meta analysis of the relationship between blood type and the risk of liver cancer in Chinese population

目的:采用Meta分析探讨中国人群中血型分布与肝癌发病风险的关系。方法:以肝癌(Liver Neoplasms[Mesh])、血型(ABO Blood-Group System[Mesh])为检索词,检索中英文数据库,系统收集相关文献。文献类型为观察性研究,由2名研究员独立筛选文献、提取数据和评价纳入文献的质量,进行Meta分析。结果:最终纳入22篇文献,共包含肝癌研究对象13729例。Meta分析结果发现,A型、B型、AB型、O型4种血型在肝癌患者中的分布与在健康人群中的分布比较,差异无统计学意义(P>0.05)。结论:血型差异在中国人群的肝癌发生风险中没有明显作用。

Objective:To explore the relationship between blood type distribution and the risk of liver cancer in Chinese population by Meta analysis.Methods:Liver Neoplasms[Mesh]and ABO Blood-Group System[Mesh]were used as the key words to search the Chinese and English databases,and the related literatures were collected systematically.The type of literature was observational study.Two researchers independently screened the literature,extracted data and evaluated the quality of the literature,and carried out Meta analysis.Results:A total of 22 literatures were included,including 13729 patients with liver cancer.The results of Meta analysis showed that there was no significant difference in the distribution of blood groups A,B,AB and O between patients with liver cancer and healthy people(P>0.05).Conclusion:The difference of blood type has no significant effect on the risk of liver cancer in Chinese population.