癌胚抗原和糖类抗原125检测对卵巢癌的诊断价值

Significance of CEA and CA125 in the diagnosis of ovarian cancer

目的探讨癌胚抗原(CEA)与肿瘤标志物糖类抗原125(CA125)检测卵巢癌的诊断价值。方法选取2019年1月至2020年1月间西安凤城医院收治的50例卵巢癌患者纳入研究组。同时期选取行健康检查的50例正常体检者纳入对照组。使用化学发光法检测两组参与者血清中CEA、CA125水平,分析其诊断卵巢癌的意义。结果研究组血清CA125和CEA水平相较于对照组明显增高,差异有统计学意义(P<0.05)。卵巢癌患者采取CEA联合CA125检测相较于单一检测诊断准确率更高,差异有统计学意义(P<0.05)。结论卵巢癌患者肿瘤标志物血清CEA、CA125水平显著上升,且CEA联合CA125可提升卵巢癌诊断准确率。

Objective To analyze the diagnostic value of carcinoembryonic antigen(CEA)and carbohydrate antigen 125(CA125)for ovarian cancer.Methods:From January 2019 to January 2020,50 ovarian cancer patients were included in a study group and 50 individuals receiving physical examination were included a control group at Fengcheng Hospital in the same period.The serum CEA and CAl25 levels were detected by electrochemiluminescence and the significance of detection of serum CEA and CAl25 levels for the diagnosis of ovarian cancer was analyzed.Results Serum CEA and CAl25 levels was significantly higher in the study group than in the control group(P<0.05).The accuracy of combined detection of CEA and CA125 was higher than that of CEA and CA125 detection alone(all P<0.05).Conclusion Serum CEA and CA125 levels increased significantly in patients with ovarian cancer and the combined detection of CEA and CA125 could improve the diagnostic accuracy for ovarian cancer.