缝合止血法和传统电凝止血法对腹腔镜下剔除卵巢良性肿瘤患者卵巢功能和妊娠率的影响

Effect of suture hemostasis and traditional electrocoagulation hemostasis on ovarian function and pregnancy rate of patients with laparoscopic removal of benign ovarian tumors

目的比较缝合止血法和传统电凝止血法对腹腔镜下剔除卵巢良性肿瘤患者卵巢功能和妊娠率的影响。方法选取接受腹腔镜卵巢良性肿瘤剔除术的86例患者作为研究对象,按照不同止血方式将86例患者分为实验组和对照组,每组43例。实验组采用缝合止血法,对照组采用传统电凝止血法。比较2组术前、术后3个月的卵泡刺激素(FSH)、雌二醇(E2)、黄体生成素(LH)水平和手术前后卵子数、卵泡数、卵巢窦卵泡数量,并比较2组患者术后1年的妊娠情况。结果术前,2组FSH、E2、LH水平比较,差异无统计学意义(P> 0.05);术后3个月,2组LH水平比较,差异无统计学意义(P> 0.05),实验组FSH水平低于术前和对照组,E2水平高于术前和对照组,差异有统计学意义(P <0.05)。术前,2组卵子数、卵泡数、窦卵泡数比较,差异无统计学意义(P> 0.05);术后,2组卵子数、卵泡数、窦卵泡数均低于术前,但实验组卵子数、卵泡数、窦卵泡数均高于对照组,差异有统计学意义(P <0.05)。实验组妊娠率为69.77%,对照组为62.79%,差异无统计学意义(P>0.05)。结论腹腔镜下卵巢良性肿瘤剔除术中采用缝合止血法对患者术后卵巢功能的影响较小,可为患者术后妊娠创造良好条件。

Objective To compare the effect of suture hemostasis and traditional electrocoagulation on ovarian function and pregnancy rate in patients with laparoscopic removal of benign ovarian tumors. Methods A total of 86 patients who underwent laparoscopic resection of benign ovarian tumors were selected,and were randomly divided into experimental group (n = 43) and control group (n = 43) according to different hemostasis methods. The experimental group was treated with suture hemostasis and the control group with traditional electrocoagulation hemostasis. The levels of follicle stimulating hormone (FSH),estradiol (E2),luteinizing hormone (LH) before and at 3 months after surgery,the number of eggs,follicles and ovarian sinus follicles before and after operation were compared. The pregnancy conditions of the two groups were compared at 1 year after operation.Results There were no significant differences in preoperative FSH,E2 and LH levels between the two groups (P > 0. 05);there was no significant difference in the LH level at 3 months after operation between the experimental group and the control group (P > 0. 05). The FSH level was significantly lower,and E2 level was significantly higher than those of preoperation and the control group (P <0. 05). There were no significant differences in the number of eggs,follicles and sinus follicles before surgery between the two groups (P > 0. 05),and the above indicators after surgery in the two groups were significantly lower than operation before (P < 0. 05),but were significantly higher in the experimental group than the control group (P < 0. 05). The pregnancy rate was 69. 77% in the experimental group and 62. 79% in the control group,but no significant difference was found in two groups (P >0. 05). Conclusion Laparoscopic removal of benign ovarian tumors by suture hemostasis has little effect on postoperative ovarian function and can be favorable for postoperative pregnancy.