摘要
将近年来国内外对中药提取物抑制NLRP3炎症小体以改善细胞焦亡从而干预动脉粥样硬化性疾病的相关研究进行概述,阐释相关中药提取物有效成分的作用特点,分析研究中所存在的问题,为动脉粥样硬化性疾病的防治提供一定参考。
This paper summarizes Chinese and foreign research on the inhibition of NLRP3 inflammasome to improve cell pyroptosis,thereby intervening the atherosclerotic diseases by Chinese materia medica(CMM) extracts in recent years,clarifies the functional characteristics of the effective components of the relevant CMM extracts,and analyzes the existing problems in the research,so as to provide some references for the prevention and treatment of atherosclerotic diseases.
作者
刘孟楠
罗钢
杨思进
LIU Mengnan;LUO Gang;YANG Sijin(Department of Cardio-cerebral Disease,Hospital of TCM Affiliated to Southwest Medical University,Luzhou,Sichuan,646000,China)
出处
《甘肃中医药大学学报》
2020年第5期91-96,共6页
Journal of Gansu University of Chinese Medicine
基金
2018年四川省科技厅项目(2018SZ0060)
2018年西南医科大学-西南医科大学附属中医医院联合项目(2018XYLH-005)
2019年泸州市科技厅项目(2019-RCM-95)。