摘要
目的观察芳香按摩疗法治疗膝关节骨性关节炎(KOA)患者的临床疗效。方法将96例KOA患者随机均分为芳香按摩组、常规按摩组和对照组,比较三组疗效,并采用ELISA法检测膝关节滑液中IL-1和TNF-α的含量。结果芳香按摩组临床治愈有效率高于对照组(90.6%vs.59.4%)(P<0.05)。与治疗前相比,芳香按摩组、常规按摩组治疗后膝关节炎指数评分、VAS疼痛评分以及IL-1和TNF-α含量均降低(P<0.05)。芳香按摩组治疗后VAS疼痛评分以及IL-1和TNF-α含量低于常规按摩组(P<0.05)。结论芳香按摩疗法可显著降低KOA患者的疼痛,并减轻膝关节的炎性反应,可作为治疗KOA安全、有效的替代辅助方法。
Objective To observe the clinical efficacy of aromatherapy in the treatment of the patients with knee osteoarthritis(KOA).Methods Ninety-six patients with KOA were randomized into three groups with 32 cases each.The patients in group A were treated with lavender aromatherapy and those in group B received routine massage.While the patients in group C did not receive any message treatment.The clinical efficacy was compared among the three groups.The expressions of IL-1 and TNF-αin knee synovial fluids were detected by ELISA method.Results The effective rate of cure in group A was higher than that in group C(90.6%vs.59.4%)(P<0.05).Compared with before,the knee joint score,VAS pain score and contents of IL-1 and TNF-αin knee synovial fluids were all significantly decreased after treatment in groups of A and B(P<0.05).Moreover,the VAS pain score and contents of IL-1 and TNF-αafter treatment in group A were less than those in group B(P<0.05).Conclusion Aromatherapy can significantly reduce the pain and inflammatory reaction of the knee joints in the patients with KOA and could be used as a safe and effective alternative adjuvant therapy for the patients with KOA.
作者
孔令丽
李文芳
谭荣莉
李晓玲
王振国
涂悦
KONG Lingli;LI Wenfang;TAN Rongli(Department of Rehabilitation,Tianjin Rehabilitation and Recuperation Center,Tianjin 300191,CHINA)
出处
《江苏医药》
CAS
2020年第10期1000-1003,1007,共5页
Jiangsu Medical Journal
基金
国家自然科学基金(81771350)
天津市科技计划项目(16ZXHLSY00120)。