急性呼吸窘迫综合征患者以驱动压为导向的机械通气策略研究进展

Advances on mechanical ventilation strategy of acute respiratory distress syndrome patients guided by drving pressure

急性呼吸窘迫综合征(acute respiratory ditress syndrome,ARDS)是一种急性弥漫性炎症性肺损伤。机械通气作为治疗ARDS的基石,目标是在维持有效氧合的基础上将呼吸机相关肺损伤降低到最小。驱动压的水平影响着ARDS患者机械通气过程中的容积伤、压力伤、生物伤、剪切伤,以驱动压为导向的呼吸机参数设置可以降低患者死亡风险,改善预后。本文就ARDS患者以驱动压为导向的机械通气策略进行综述。

Acute respiratory distress syndrome(ARDS)is an acute diffuse inflammatory lung injury.Mechanical ventilation is the cornerstone of the treatment from ARDS,which aims to minimize ventilator-induced lung injury while maintaining effective oxygenation.The level of driving pressure affects the volume injury,pressure injury,biological injury and shearing injury during mechanical ventilation of ARDS patients.This study reviewed the mechanical ventilation strategy with driving pressure as guidance in ARDS patients.