自体脂肪填充联合A型肉毒毒素注射在面部年轻化的效果

Clinical application of autologous fat grafting combined with botulinum toxin A injection in facial rejuvenation

目的观察自体脂肪填充联合A型肉毒毒素注射在面部年轻化的效果。方法2018年10月至2019年9月,北京清华长庚医院整形外科就诊的女性美容就医者14例,年龄27~64岁,平均38岁。选取腰腹部或大腿内侧作为脂肪供区,用负压吸脂机或20 ml负压注射器获取脂肪颗粒;多层次、多隧道、多点、少量、低压、缓慢均匀注射填充额部、颞部、眉弓、眉间、颧颊部、鼻唇沟、木偶纹、颏部等面部凹陷处;同时行面部A型肉毒毒素注射。结果术后随访3~12个月,13例美容就医者注射1次填充即达满意效果,1例美容就医者注射填充2次达到满意效果。面部各部位比例更加协调,局部凹陷得到纠正,面部皱纹减轻,皮肤质地、色泽提升;无严重并发症出现。结论自体脂肪填充联合A型肉毒毒素注射可起到较好的面部年轻化效果,值得临床应用。

Objective To observe the effect of autologous fat filling combined with botulinum toxin A injection for facial rejuvenation.Methods From October 2018 to September 2019,14 patients treated with autologous fat filling and botulinum toxin A injection were analyzed retrospectively.The fat granule was harvested by liposuction from waist abdomen or lateral thigh under intravenous anesthesia and local infiltration anesthesia.After purified,the fat was filled into the forehead,temps,eyebrow,glabella,zygomatic,cheek,nasolabial fold,marionette lines and chin in 14 patients with multiple-layer,multiple-tunnel,multiple-point and low-amount injection with even speed slowly.Botulinum toxin A was injected at the same time,10~20 u in forehead wrinkles;8-12 u in glabellar wrinkles;6-12 u in Crow's feet;1-4 u in marionette lines and 4 u in depressor muscle.Results After 3-12 months follow-up,14 cases achieved the expected effect by injecting once and 1 cases achieved satisfactory results after reoperation.The proportion of all parts of the face was more harmonious,the local depression was corrected,the facial wrinkles were reduced,and the skin texture and color were improved.No serious complications occurred.Conclusions Autogenous fat filling combined with botulinum toxin A injection can enhance the facial rejuvenation,which is worth spreading in clinical practice.