242例垂体泌乳素腺瘤中医证候分布的临床研究

Clinical Study on the Distribution of TCM Syndromes in 242 Cases of Pituitary Prolactinoma

目的探讨泌乳素腺瘤患者中医症候分布特点。方法采用中医症候临床调查表,收集符合诊断和纳入标准的中医症候四诊信息资料;通过运用描述性分析和聚类分析,探讨各中医证候下四诊信息分布特点。结果垂体泌乳素腺瘤中医证型气血亏虚证、脾肾阳虚证、痰瘀互结证、肝肾阴虚证最为常见。发病相关危险因素包括年龄、病程、睡眠和情志,其年龄、病程分布与中医证型之间存在相关性。结论明确垂体泌乳素腺瘤中医证型分布规律,对指导临床用药有重要的现实意义。

Objective To study the clinical effect of traditional Chinese medicine prescription combined with ursodeoxycholic acid in the treatment of intrahepatic cholestasis of pregnancy(ICP).Methods From February 2016 to February 2018,100 patients with ICP in the Second Affiliated Hospital of XiThis study of pituitary adenoma in patients with symptoms,diagnostic data,investigation of general situation,explore the prolactinoma TCM syndrome distribution characteristics using SPSS statistical software,and to explore the characteristics of the distribution of TCM symptoms in patients with prolactinoma.Methods Use the clinical questionnaire of TCM syndromes to collect the four-diagnosis information data of TCM syndromes that meet the diagnosis and inclusion criteria;use descriptive analysis and cluster analysis to explore the characteristics of the four-diagnosis information distribution of each TCM syndrome.Results Pituitary prolactinoma TCM syndrome type Qi and blood deficiency syndrome,spleen and kidney yang deficiency syndrome,phlegm and blood stasis mutual syndrome,liver and kidney yin deficiency syndrome are the most common.Risk factors related to disease include age,disease course,sleep and emotions.There is a correlation between age,disease course distribution and TCM syndrome types.Conclusion To clarify the distribution of TCM syndrome types of pituitary prolactinoma has important practical significance for guiding clinical medication.