功能性消化不良发病机制及治疗的研究进展

Research progress in the pathogenesis and treatment of functional dyspepsia

功能性消化不良(FD)是一种常见的功能性胃肠道疾病,根据罗马Ⅵ标准分为餐后不适综合征(PDS)和上腹疼痛综合征(EPS)两大类。FD具有多种病理生理机制,如内脏敏感性升高、胃容受性受损和胃排空延迟等。因为FD发病率高、症状多样化、反复发作等特点,对患者的生活质量和身心造成了负面影响。本文结合研究进展,对FD的发病机制及治疗进行一综述。

Functional dyspepsia(FD)is a common functional gastrointestinal disease,including postprandial distress syndrome(PDS)and epigastric pain syndrome(EPS)according to RomeⅥstandard.FD has many pathophysiological mechanisms including increased visceral sensitivity,impaired gastric accommodation and delayed gastric emptying.FD is characterized by high incidence,diverse symptoms and recurrent attacks,which has negative effect on the quality of life and on the physical and psychological health of the patients.We make a complete conclusion about the pathogenesis and treatment of FD in this review.