研究妊娠不同时期D-二聚体、凝血四项的变化

Study on the Changes of D-dimer and Four Items of Coagulation in Different Periods of Pregnancy

目的研究孕妇妊娠不同时期血浆D-二聚体、凝血四项变化及检验价值。方法取2018年4月—2020年2月接收80例妊娠不同时期孕妇(试验组),同期选择健康体检非妊娠女性20例(对照组)研究,120例受检者均实施血浆D-二聚体(D-D)、凝血四项(凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原)检查,对比两组检查结果。结果试验组D-D、FIB较对照组高,临产期组D-D、FIB较妊娠早、中、晚期组高(P<0.05)。试验组PT、APTT、TT较对照组低,临产期组PT、APTT、TT较妊娠早、中、晚期组低(P<0.05)。结论孕妇妊娠不同时期实施D-二聚体、凝血四项可帮助医师详细了解孕妇血液状态,并根据检验结果制定有效干预方案,提高孕妇分娩安全性。

Objective To study the changes and test value of plasma D-dimer and coagulation in different stages of pregnancy.Methods From April 2018 to Feburary 2020,80 pregnant women(test group)at different stages of pregnancy were selected.At the same time,20 healthy(non-pregnant)women(control group)were selected for health examination.Plasma D-D and four items of blood coagulation(prothrombin time,activated partial thromboplastin time,thrombin time,fibrinogen)of 120 were compared,and the results of the two groups were compared.Results The D-D and FIB in the experimental group were higher than those in the control group,and the D-D and FIB in the labor group were higher than those in the early,middle and late pregnancy groups(P<0.05).The PT,APTT and TT in the experimental group were lower than those in the control group,and the PT,APTT and TT in the labor group were lower than those in the early,middle and late pregnancy groups(P<0.05).Conclusion The implementation of D-dimer and coagulation at different stages of pregnancy in pregnant women can help physicians understand the blood status of pregnant women in detail,and formulate effective intervention plans based on the test results to improve the safety of pregnant women's delivery.