嗜麦芽窄食假单胞菌感染对老年肺炎患者预后的影响

The influence of Stenotrophomonas maltophilia infection on the prognosis of elderly patients with pneumonia

目的探讨下呼吸道嗜麦芽窄食假单胞菌感染对老年肺炎患者预后的影响。方法对1837例老年肺炎患者进行分析。通过电子病历收集患者基础疾病、实验室检查、30 d预后等临床信息。分析影响老年肺炎患者30 d病死率的独立危险因素。结果下呼吸道标本分离出嗜麦芽窄食假单胞菌患者30 d病死率明显高于未分离出嗜麦芽窄食假单胞菌患者(23.84%vs.11.51%,P<0.05)。年龄≥85岁、合并肿瘤、清蛋白<30 mg/L、尿素氮≥7.14 mmol/L及嗜麦芽窄食假单胞菌感染是影响肺炎患者30 d病死率的独立危险因素(P<0.05)。结论嗜麦芽窄食假单胞菌感染与老年肺炎患者30 d病死率明显相关,可作为其短期预后的独立预测因子。

Objective To discuss the influence of Stenotrophomonas maltophilia infection on the prognosis of elderly patients with pneumonia.Methods A total of 1837 elderly patients were included in this study.All clinical data including underlying disease,laboratory tests and 30-days mortality were collected from electronic medical records.The risk factors of influenced 30-days mortality were analyzed using Kaplane-Meier analysis.Results The 30-days mortality rate of the patients with Stenotrophomonas maltophilia infection was significantly higher than patients without Stenotrophomonas maltophilia infection(23.84%vs.11.51%,P<0.05).85 years old or order,with tumor,albumin<30 mg/L,urea nitrogen≥7.14 mmol/L and Stenotrophomonas maltophilia infection were independent risk factor influencing 30-days mortality.Conclusion Stenotrophomonas maltophilia infection is obviously associated with 30-days mortality in elderly patients with pneumonia,which could be an independent for short-term prognosis.