面向国产处理器大数据一体机的基因压缩技术研究

Research on genome compression technologies for domestic processor big data machine

大数据一体机作为大数据时代的基础设施,其自主安全可控显得尤为重要。基因数据因其巨大的社会价值、经济价值及军事价值,其安全是国家安全的一部分。因此,存储、分析与处理基因数据是国产处理器大数据一体机的重要应用之一。文中首先介绍了国产处理器大数据一体机和基因序列文件主要格式,然后分为无参考序列基因压缩算法和基于参考序列基因压缩算法综述了FASTA格式基因数据压缩技术及基因压缩并行化技术的发展历程和研究现状,同时在国产处理器大数据一体机上验证了近年来优秀基因压缩算法的性能。研究面向国产处理器大数据一体机的基因压缩技术对解决基因数据安全和基因压缩技术自主可控具有很重要的意义,也为我国基因处理技术的全面国产化提供了参考。

As an infrastructure in the era of big data,an independent,safe and controllable big data ma­chine is particularly important.Because of its huge social value,economic value and military value,ge­nomic data are a part of national security.Therefore,storing,analyzing and processing genomic data is one of the important applications of the domestic processor big data machine.This paper firstly introduces the domestic processor big data machine and the main file formats of the genome sequence,and then reviews the reference-free genome compression algorithms and the reference-based genome compression algo­rithms.Meanwhile,the paper verifys the performance of the state-of-the-art genome compression algorithms in recent years on the domestic processor big data machine.The research on the genome compression technology for domestic processor big data machine is of great significance to solving the safety problems of genomic data and the independent control of the genome compression technology.The technology pro­vides a reference for the domestic production of genome processing technologies in China.