中药治疗痛风性关节炎实验研究进展

Research on the experimental progress of traditional Chinese medicine treating gouty arthritis

综述近年中药治疗痛风性关节炎(gouty arthritis,GA)的实验研究文献,发现目前普遍沿用或改良经典造模方法,且对病证结合模型及细胞模型有一定探索,但对病证结合模型的应用仍较少;作用机制研究方面,单味中药、中药提取物、中药复方在抑制炎症反应、调节信号通路、抗氧化、降尿酸、提高痛阈及调节机体代谢等多个方面发挥治疗GA的作用。

This article reviewed and summarized the experimental researches on the treatment of gouty arthritis(GA)with traditional Chinese medicine in recent years,which showed that the traditional or modified animal models of disease were widely used,and also concerned about the the model of integrating the disease and symptoms.However,few are about the application of combined disease and syndromes model.The mechanism research result shows that,single Chinese herb,component extract of Chinese herbs and Chinese herbal compound all play an important role in inhibiting inflammation,regulating signal pathway,anti-oxidation,reducing uric acid,increasing feeling of pain and regulating body metabolism.