近二十年我国杀虫剂毒理学研究进展(Ⅱ)——昆虫对杀虫剂的抗性研究

Advances in insecticide toxicology in China in the last two decadesⅡ:Resistance of insects to insecticides

本文综述了中国昆虫学家、杀虫剂毒理学研究者与植物保护专家及害虫防治工作者最近20年来在昆虫对杀虫剂的抗性研究方面的进展,并就杀虫剂施用后害虫抗药性的发生、交互抗性的形成、杀虫剂增效剂的使用以延缓抗性的发展做了简要介绍,特别对昆虫抗药性的产生机制,包括靶标抗性、代谢抗性和穿透抗性在内的抗性机理,尤其是细胞色素P450酶系、乙酰胆碱酯酶(AChE)、谷胱甘肽巯基转移酶(GST)、电压门控钠离子通道(VGSC)、P-糖蛋白(P-gp)、乙酰胆碱受体(AChR)、表皮生长因子受体(EGFR)和g-氨基丁酸受体(GABAR)等与杀虫剂抗性相关的基因及其表达产物在昆虫抗药性形成中的作用的研究进行了系统性综述。

Advances in research on the resistance of insects to insecticides made by entomologists,insecticide toxicologists,plant protection and pest control experts in China over the past 20 years is reviewed.Insecticide resistance,including cross-resistance and the delay,or prevention,of resistance by applying different insecticides with synergistic effects,is briefly introduced.Studies on the mechanisms of insecticide resistance in insects,including target resistance,metabolic resistance,and penetration resistance,especially the role of the genes such as cytochrome P450s,acetylcholinesterase(AChE),glutathione S-transferase(GST),voltage-gated sodium channel(VGSC),P-glycoprotein(P-gp),actylcholine receptor(AChR),epidermal growth factor receptor(EGFR),andγ-aminobutyric acid receptor(GABAR),and their expression products in the development of resistance,are systematically reviewed.