儿童功能性消化不良药物治疗的研究进展

Research Progress of Drug Therapy for Functional Dyspepsia in Children

目前,功能性消化不良(FD)的治疗效果仍不理想,尤以儿童FD更甚。药物治疗是FD主要的治疗手段,常用的药物主要包括抑酸剂、促动力剂、助消化药等,通过药物治疗达到缓解患儿临床症状、恢复患儿正常生理功能的目的。随着神经胃肠病学、功能性影像学、心理学等学科的发展,儿童FD被重新认识,各类型治疗药物的研发也有了新的进展,包括多种西药的发现和中药的研制。但目前尚无一种药物可以使FD患儿的症状得到完全缓解,而且缺少统一有效的治疗方案。在未来仍需继续进行研究与观察,寻找更为理想的药物治疗方案,以帮助提高获益,改善患儿的预后。

At present,the therapeutic effect of functional dyspepsia(FD) is still not ideal,especially in the children patients.Drugs are the main treatment for FD,including acid inhibitors,prokinetics,digestive aids,etc.The purpose of alleviating the children’s clinical symptoms and restoring their normal physiological functions is achieved through drug treatment.With the development of neurogastroenterology,functional imaging,psychology and other disciplines,children’s FD has been re-understood,and various types of therapeutic drugs have gradually made new progress,including the discovery of a variety of western medicines and the development of Chinese medicines.However,there is no drug that can help children with FD to achieve complete remission of symptoms,and there is still a lack of unified and effective treatment plan for the disease.In the future,research and observation are still needed to find more ideal drug treatment options so to help increase the benefits and improve the prognosis of the children patients.