摘要
目的探究供精人工授精(AID)不良妊娠结局类型的影响及预测指标。方法对2009年11月至2019年6月实施的AID周期中的67个生化妊娠周期与90个早期流产周期的周期特点进行了回顾性分析。结果2种不良妊娠结局的人工授精(AI)后14 d血清β-绒毛膜促性腺激素(HCG)水平及比例分布差异有统计学意义(P<0.01),早期流产患者的平均不孕年限显著长于生化妊娠患者(P<0.05),其余周期特点评价指标在2种不良妊娠组间的差异均无统计学意义(P>0.05)。结论患者AI后14 d血清β-HCG水平、不孕年限、AI日子宫内膜形态可作为行AID助孕后不良妊娠结局类型的(潜在)预测指标。至于其具体影响效果及应用价值,仍需进一步研究。
Objective To investigate the impacts and predictors of the adverse pregnancy outcomes in artificial insemination by donor(AID).Methods A retrospective statistical analysis was performed to compare the characteristics of 67 biochemical pregnancy cycles and 90 early abortion cycles in AID between November 2009 and June 2019.Results Between these two adverse pregnancy outcomes,there was a significant difference in the value and distribution of serum β-HCG levels at 14 days after AID(P<0.01).The mean length of infertility was significantly longer in patients with early abortion than those with biochemical pregnancy(P<0.05).The remaining indicators of cycle characteristics did not differ between the two adverse pregnancy outcomes(P>0.05).Conclusion The 14-day serum β-HCG level,length of infertility,and endometrial morphology on the day of AI may be used as potential preditors of adverse pregnancy outcomes after AID.Further studies are needed to determine their specific impacts and clinical value.
作者
史雅萍
郝伟明
梁云霞
王莉莉
李艳梅
宋海霞
张晓花
姬英英
郭兴萍
Shi Yaping;Hao Weiming;Liang Yunxia;Wang Lili;Li Yanmei;Song Haixia;Zhang Xiaohua;Ji Yingying;Guo Xingping(Business Department,Shanxi Institute of Reproductive Sciences,Taiyuan 030006,China;不详)
出处
《中国药物与临床》
CAS
2020年第21期3548-3551,共4页
Chinese Remedies & Clinics
基金
山西省卫生健康委科研课题(2019003)。
关键词
授精
人工
生化妊娠
早期流产
绒毛膜促性腺激素
β亚单位
人
妊娠结局
Insemination,artificial
Biochemical pregnancy
Early abortion
Chorionic gonadotropin,beta subunit,human
Pregnancy outcome