摘要
目的:探讨亲水性纤维含银敷料联合负压封闭引流对深Ⅱ度烧伤患者创面愈合质量及血管内皮生长因子(Vascular endothelial growth factor,VEGF)的影响。方法:选择2017年6月-2018年6月笔者医院收治的深Ⅱ度烧伤患者120例进行研究,以随机数表法分为观察组(n=62)和对照组(n=58)。对照组给予负压封闭引流治疗,观察组给予亲水性纤维含银敷料联合负压封闭引流治疗。比较两组患者的临床疗效、创面愈合时间、创面愈合率、VEGF水平、换药次数、住院时间、住院费用、换药疼痛、瘢痕评分及色素沉着发生情况。结果:治疗后,观察组愈合总有效率为91.94%高于对照组的70.69%,差异具有统计学意义(P<0.05)。治疗前,两组VEGF水平比较差异无统计学意义(P>0.05);治疗后,两组VEGF水平均显著改善,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组创面愈合时间显著低于对照组,差异有统计学意义(P<0.05)。治疗后,两组住院费用比较差异无统计学意义(P>0.05)。观察组换药次数、住院时间显著低于对照组,差异有统计学意义(P<0.05);观察组换药疼痛评分、瘢痕评分及色素沉着率均显著低于对照组,差异具有统计学意义(P<0.05)。结论:在深Ⅱ度烧伤患者中应用亲水性纤维含银敷料联合负压封闭引流效果显著,可有效改善患者创面愈合质量、VEGF水平,且不增加治疗费用。
Objective To investigate the effect of hydrophilic fiber silver dressing combined with vacuum sealing drainage on wound healing quality and vascular endothelial growth factor(VEGF)in patients with deep second degree burn.Methods 120 patients with deep second degree burn were selected for study,from June 2017 to June 2018,were divided into the observation group(n=62)and the control group(n=58)by the random number table method.The control group was treated with negative pressure closed drainage,while the observation group was treated with hydrophilic fiber containing silver dressing combined with negative pressure closed drainage.The clinical efficacy,wound healing time,wound healing rate,VEGF,dressing change frequency,hospitalization time,hospitalization cost,dressing pain,scar score and occurrence of pigmentation in the two groups were compared.Results After treatment,the total effective rate of the observation group was 91.94%,higher than that of the control group(70.69%),the difference was statistically signifi cant(P<0.05).Before treatment,there was no signifi cant difference in VEGF levels between the two groups(P>0.05).After treatment,VEGF levels in both groups were signifi cantly improved,and the observation group was lower than the control group(P<0.05).The wound healing time of the observation group was signifi cantly lower than that of the control group(P<0.05).After treatment,there was no signifi cant difference in hospitalization expenses between the two groups(P>0.05).The times of dressing change and hospitalization time in the observation group were signifi cantly lower than those in the control group(P<0.05).The pain score,scar score and pigmentation rate of the observation group were signifi cantly lower than those of the control group(P<0.05).Conclusion Application in patients with deep second degree burns hydrophilic fiber containing silver dressings joint closed negative pressure drainage effect is remarkable,which can effectively improve the quality of patients with wound healing and VEGF,and does not increase the cost of treatment.
作者
梁云
张国安
LIANG Yun;ZHANG Guo-an(Department of Burn,Beijing Jishuitan Hospital,Beijing 100035,China)
出处
《中国美容医学》
CAS
2020年第11期38-41,共4页
Chinese Journal of Aesthetic Medicine
关键词
亲水性纤维含银敷料
负压封闭引流
烧伤
深Ⅱ度
创面修复
血管内皮生长因子
hydrophilic fiber silver dressing
vacuum sealing drainage
burn
deep second degree
wound repair
vascular endothelial growth factor