摘要
磁共振指纹(MRF)技术是一种新的基于MRI的定量成像方法,使用伪随机采集方法,同时从不同组织获得具有唯一属性的"指纹",并使用模式识别进行后处理,得到感兴趣区的指定参数量化图。与传统MRI比较,MRF具有信噪比和效率更高能进行多参数定量测量等优势,可应用于大部分传统MRI的应用场合。文中对MRF技术在脑组织定量成像方面的研究进展作综述,对基于MRF的脑组织参数测量和MRF在脑疾病中的应用等方面进行归纳和总结。
Magnetic resonance fingerprinting(MRF) technology is a new quantitative imaging method based on MRI. It uses a pseudo-random acquisition method, simultaneously obtains "fingerprints" with unique attributes from different organizations, and uses pattern recognition for post-processing to obtain a quantified map of the specified parameters of the area of interest. Compared with traditional MRI, MRF has the advantages of higher signal-to-noise ratio, higher efficiency, and multi-parameter quantitative measurement. It can be applied to most of applications of traditional MRI. The research progress of MRF technology in brain tissue quantitative imaging were reviewed, and the measurement of brain tissue parameters based on MRF and the application of MRF technology in brain diseases were summarized.
作者
冷一峻
吴秋雯
李郁欣
夏威
耿道颖
杨丽琴
LENG Yi-jun;WU Qiu-wen;LI Yu-xin;XIA Wei;GENG Dao-ying;YANG Li-qin(Academy for Engineering&Technology,Fudan University,Shanghai 200082,China;Department of Radiology,Huashan Hospital,Fudan University,Shanghai 200040,China;Institute of Functional and Molecular Medical Imaging,Fudan University,Shanghai 200082,China)
出处
《中国临床神经科学》
2020年第5期579-583,共5页
Chinese Journal of Clinical Neurosciences
基金
上海市科学技术委员会科技创新行动计划生物医药科技支撑专项项目(编号:20S31904300)
上海市科学技术委员会科技创新行动计划临床医学领域项目(编号:19411951200)
复旦大学2019国家重大项目预研(先导)(编号:IDH2310019)
复旦大学上海医学院“临床医学研究领航项目”(编号:DGF501022/015)
苏州市科技计划项目(编号:SYG201908)。
关键词
磁共振指纹
定量成像
多参数成像
脑疾病
magnetic resonance fingerprinting
quantitative imaging
multi-parameter imaging
brain disease
