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肠道菌群代谢物调控糖脂代谢及其在动物生产中的应用研究进展 被引量:4

Research Progress on the Regulation of Glycolipid Metabolism by Intestinal Microflora Metabolites and Its Application in Animal Production
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摘要 肠道菌群参与机体营养代谢过程,其主要代谢物短链脂肪酸(SCFAs)、次级胆汁酸和脂多糖(LPS)通过识别G蛋白偶联受体、Toll样受体等相关受体,从而调控糖脂代谢通路和相关基因表达,影响动物健康和代谢平衡。本文就SCFAs、次级胆汁酸和LPS对宿主糖脂代谢的调控作用及其在动物生产上的影响进行综述,旨在为预防和治疗畜禽糖脂代谢紊乱、提高畜禽养殖效率提供新思路。 Intestinal microflora is involved in the process of nutritional metabolism.The main metabolites short chain fatty acids(SCFAs),secondary bile acids and lipopolysaccharides(LPS)regulate the glycolipid metabolism pathway and the expression of related factors by identifying related receptors,such as G protein coupled receptors(GPRs)and toll like receptors(TLRs),which affect animal health and metabolic balance.In this paper,SCFAs,secondary bile acids and LPS on the regulation of host glycolipid metabolism and its impact on animal production were reviewed to prevent and treat the disorder of glycolipid metabolism in livestock and improve the efficiency of livestock breeding.
作者 章娜 张海波 黎力之 廖晓鹏 关玮琨 郭冬生 ZHANG Na;ZHANG Haibo;Li Lizhi;LIAO Xiaopeng;GUAN Weikun;GUO Dongsheng(College of Life Science and Resources and Environment,Engineering Technology Research Center of Jiangxi Universities and Colleges for Selenium Agriculture,Yichun Key Laboratory of Functional Agriculture and Ecological Environment,Yichun University,Jiangxi Yichun 336000,China;School of Continuing Education,Yichun University,Jiangxi Yichun 336000,China)
出处 《中国畜牧杂志》 CAS 北大核心 2020年第11期38-43,共6页 Chinese Journal of Animal Science
基金 国家地区科学基金项目(32060773) 江西省自然科学基金(20202BABL205010) 江西省现代农业产业技术体系建设专项资金资助(JXARS-14) 宜春学院科研发展基金项目(kyfzl2020008) 江西省教育厅项目(GJJ190848)。
关键词 肠道菌群 菌群代谢物 糖脂代谢 信号通路 动物生产 Intestinal microbiota Bacterial metabolites Glycolipid metabolism Signaling pathway Animal production
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