关注餐后血糖,预混胰岛素助力多维度血糖管理

Focus on Postprandial Plasma Glucose,Premixed Insulin Helps Multi-dimensional Blood Glucose Management

餐后血糖(Postprandial Plasma Glucose,PPG)升高是中国2型糖尿病(Type 2 Diabetes Mellitus,T2DM)的重要临床特征之一。PPG升高可导致血糖波动增加,进一步加速疾病进展。相较空腹血糖(Fasting Plasma Glucose,FPG),PPG升高与糖尿病并发症及死亡的发生风险显著相关。因此,早期、有效干预餐后血糖、防止T2DM进展是我国T2DM血糖管理的重点。以门冬胰岛素30为代表的预混胰岛素类似物包含餐时和基础胰岛素,可以同时控制PPG和FPG,减少血糖波动幅度。同时基于中国数据分析显示,门冬胰岛素30与其他胰岛素治疗方案相比,能够节省治疗费用,总治疗成本更低,更好惠及糖尿病患者。

Elevated postprandial plasma glucose(PPG)is one of the important clinical features of patients with Type 2 Diabetes Mellitus(T2DM)in China.Elevated PPG can lead to increased blood glucose fluctuations,further accelerating disease progression.Compared with Fasting Plasma Glucose(FPG),elevated PPG is significantly associated with increased risk of complications of diabetes and mortality.Therefore,early and effective intervention of postprandial blood glucose to prevent progression of T2DM is the focus of T2DM management in our country.The premixed insulin analogues represented by insulin aspart 30 contain mealtime and basal insulin,which can control PPG and FPG at the same time and reduce the fluctuation of blood glucose.Meanwhile analysis based on Chinese data showed that insulin aspart 30 could save treatment costs,lower total treatment costs,and give diabetic patients more benefits compared with other insulin treatment regimens.