2型糖尿病患者合并亚临床甲状腺功能减退症对颈动脉粥样硬化的影响

The Effect of Type 2 Diabetes Patients with Subclinical Hypothyroidism on Carotid Atherosclerosis

目的分析亚临床甲状腺功能减退症合并2型糖尿病患者的动脉粥样硬化产生的影响。方法选取该院于2018年3月—2019年9月收治的2型糖尿病合并亚临床甲状腺功能减退症患者86例作为该次研究的观察组,选取该院收治的86例单纯2型糖尿病患者作为该次研究的对照组。对两组患者的血糖、血脂等指标以及两组患者颈动脉动脉粥样硬化的发生情况进行分析对比。结果观察组患者中,其甘油三酯、总胆固醇及促甲状腺激素水平明显比对照组患者高,差异有统计学意义(P<0.05);观察组患者的动脉粥样硬化发生率比对照组高,其主要危险因素为促甲状腺激素。结论2型糖尿病合并亚临床甲状腺功能减退症患者较单纯2型糖尿病患者更易发生动脉粥样硬化,动脉粥样硬化的发生与亚临床甲状腺功能的减退存在相关性。

Objective To analyze the effect of subclinical hypothyroidism combined with type 2 diabetes on atherosclerosis in patients with type 2 diabetes.Methods 86 patients with type 2 diabetes and subclinical hypothyroidism treated in the hospital from March 2018 to September 2019 were selected as the observation group in this study,and 86 patients with type 2 diabetes treated in our hospital were selected as the observation group.The control group for this study.The blood glucose,blood lipid and other indicators of the two groups of patients and the incidence of carotid atherosclerosis in the two groups were analyzed and compared.Results In the observation group,the levels of triglyceride,total cholesterol and thyroid-stimulating hormone were significantly higher than those in the control group,the difference was statistically significant(P<0.05).The incidence of atherosclerosis was higher in the observation group than in the control group;the main risk factor was thyroid-stimulating hormone.Conclusion Patients with type 2 diabetes and subclinical hypothyroidism are more likely to develop atherosclerosis than patients with type 2 diabetes.The incidence of atherosclerosis is related to hypoclinical hypothyroidism.