子宫内膜异位症和子宫腺肌病与复发性流产

Endometriosis,adenomyosis and recurrent spontaneous abortion

子宫内膜异位症和子宫腺肌病是妇科常见疾病。越来越多的证据表明,这两种疾病对生殖功能有重要影响。临床可表现为不孕不育和流产等,尤其是早期流产。子宫内膜异位症引起流产的原因主要有疾病导致的内分泌功能异常、子宫内膜容受性降低和免疫因素等。子宫腺肌病导致流产的机制主要是子宫螺旋动脉重塑受损和子宫结合带结构功能异常。临床应注重自然流产患者子宫内膜异位症和子宫腺肌病的有关筛查与诊断,并在下次妊娠前给予积极的治疗。

Endometriosis and adenomyosis are two common gynecological diseases.More and more evidences have shaown that these two diseases have important effects on reproduction,being manifestated as infertility and spontaneous abortion clinically,especially abortion in the first trimester.The main causes of spontaneous miscarriage induced by endometriosis are endocrine dysfunction,decreased endometrial receptivity and immune factors.The mechanisms of spontaneous miscarriage caused by adenomyosis are damaged uterine spiral artery remodeling and abnormal structure and function of uterine junction zone.We should pay attention to the screening and diagnosis of endometriosis and adenomyosis in patients with spontaneous abortion,and active treatment is recommended before next pregnancy.