比较去乙酰毛花苷注射液、胺碘酮治疗急诊危重症合并快速心律失常的临床效果

Comparing the Clinical Effects of Deacetyl Lanolin Injection and Amiodarone in the Treatment of Critically ill Patients with Tachyarrhythmia

目的针对急症危重症合并快速心律失常患者分别采用胺碘酮、去乙酰毛花苷注射液进行治疗的具体效果进行分析。方法按照对比治疗的方式展开该次研究,2019年1—12月所选入该院患者共计88例,按照随机抽选的方式取组中44例,在常规治疗的基础上以去乙酰毛花苷注射液进行治疗,作为对照组,余下患者则辅助以胺碘酮进行治疗,作为观察组。针对两组患者恢复情况进行分析。结果结合对两组整体疗效进行评估,观察组以97.73%(43/44)明显高于对照组81.82%(36/44),差异有统计学意义(χ^2=4.456,P<0.05);结合对两组恢复窦性心律用时、左心室舒张末期直径、舒张早期充盈峰速度以及左心室射血分数进行对比,观察组均存在有明显优势,差异有统计学意义(t=17.326、17.034、35.364、23.413,P<0.05)。观察组在恢复过程中仅4例出现并发症,而对照组则有11例出现并发症,观察组发生率明显较低,差异有统计学意义(χ^2=8.892,P=0.001)。结论针对急诊危重症合并快速心律失常患者按照胺碘酮进行治疗,可促使患者心功能在较短时间内得到改善,对于稳定患者病情,帮助患者恢复等均存在有极为重要的意义。

Objective To analyze the specific effects of treatment with amiodarone and deacetyl lanolin injection in patients with acute and critical illness combined with tachyarrhythmia.Methods The study was carried out according to the method of comparative treatment.A total of 88 patients were selected by the hospital from January to December 2019.44 patients in the group were selected according to the method of random selection,and they were treated in routine treatment.On the basis of the treatment,deacetyl lanolin injection was used as the control group,and the remaining patients were treated with amiodarone as the observation group.The recovery situation of the two groups of patients was analyzed.Results The overall curative effect of the two groups was evaluated in combination.The observation group was 97.73%(43/44)significantly higher than the control group 81.82%(36/44),the difference was statistically significant(χ2=4.456,P<0.05);combined with the recovery of sinus rhythm,the left ventricular end-diastolic diameter,early diastolic filling peak velocity and left ventricular ejection fraction in the two groups,the observation group had obvious advantages,the difference was statistically significant(t=7.326,17.034,35.364,23.413,P<0.05).In the observation group,only 4 cases had complications during the recovery process,while 11 cases in the control group had complications.The comparison showed that the observation group had a significantly lower incidence,the difference was statistically significant(χ2=8.892,P=0.001).Conclusion Amiodarone treatment for emergency critically ill patients with tachyarrhythmia can improve the cardiac function of patients in a short period of time,which is extremely important for stabilizing the patient's condition and helping patients to recover.