老年原发性高血压患者应用降压药物的效果及药学分析

Application and pharmaceutical analysis of antihypertensive drugs in elderly patients with essential hypertension

目的:探讨老年原发性高血压患者降压药物的应用效果及药学分析。方法:2018年6月-2019年6月收治老年原发性高血压患者240例,收集并整理所有患者临床资料、降压药物使用情况,分析其临床疗效及药物不良反应情况。结果:临床降压药物使用中,氨氯地平使用率最高(38.75%),其次为缬沙坦(31.67%)、贝那普利(12.92%)。用药治疗后,临床总有效率为76.67%;各类降压药物临床总有效率均在75%以上;治疗期间共发生药物不良反应24例(10.00%)。结论:老年原发性高血压患者确诊后,应依据患者个体情况为其制定安全有效的降压药物治疗方案,以提高老年患者临床治疗效果,改善其预后生活质量。

Objective:To explore the application effect and pharmaceutical analysis of antihypertensive drugs in elderly patients with essential hypertension.Methods:From June 2018 to June 2019,240 cases of elderly patients with essential hypertension were selected.Clinical data of all the patients and the use of antihypertensive drugs were collected and collated,and their clinical efficacy and adverse drug reactions were analyzed.Results:In the clinical use of antihypertensive drugs,the use rate of amlodipine was the highest(38.75%),followed by valsartan(31.67%)and benazepril(12.92%).The total effective rate was 76.67%after medication.The total effective rate of various types of antihypertensive drugs is above 75%.A total of 24 cases(10.00%)had adverse drug reactions during the treatment.Conclusion:After the diagnosis of elderly patients with essential hypertension,safe and effective antihypertensive drug therapy should be formulated according to the individual condition of patients,so as to improve the clinical treatment effect of elderly patients and improve their prognostic quality of life.