噻托溴铵联合布地奈德福莫特罗对改善慢性阻塞性肺疾病患者睡眠质量的分析

Analysis of tiotropium bromide combined with budesonide formoterol on the improvement of sleep quality in patients with chronic obstructive pulmonary disease

目的:分析噻托溴铵联合布地奈德福莫特罗对改善慢性阻塞性肺疾病患者睡眠质量的效果。方法:2017年10月-2019年9月收治慢性阻塞性肺疾病患者48例,根据治疗方法不同分为两组进行分组治疗探讨,两组各24例。对照组采用噻托溴铵吸入治疗;试验组在噻托溴铵基础上联合布地奈德福莫特罗治疗。比较两组患者治疗前后肺功能指标水平变化及睡眠质量(PSQI)评分。结果:试验组治疗后肺功能各项指标水平均优于对照组,差异有统计学意义(P<0.05);试验组治疗后PSQI评分显著低于对照组,差异有统计学意义(P<0.05)。结论:噻托溴铵联合布地奈德福莫特罗治疗慢性阻塞性肺疾病,能有效促进患者肺功能恢复,改善或消除患者呼吸困难症状,进一步促进患者睡眠质量提升。

Objective:To analyze the effect of tiotropium bromide combined with budesonide formoterol on the improvement of sleep quality in patients with chronic obstructive pulmonary disease.Methods:from October 2017 to September 2019,48 patients with chronic obstructive pulmonary disease were selected and divided into two groups according to different treatment methods,with 24 cases in each group.The control group was treated with tiotropium bromide inhalation;the experimental group was treated with tiotropium bromide combined with budesonide formoterol.The changes of pulmonary function indexes and sleep quality(PSQI)scores were compared between the two groups before and after treatment.Results:The lung function index levels after treatment of the experimental group were all better than the control group,with the difference was statistically significant(P<0.05).PSQI score of the experimental group after treatment was significantly lower than the control group,with the difference was statistically significant(P<0.05).Conclusion:Tiotropium bromide combined with budesonide formoterol can effectively promote the recovery of pulmonary function in patients with chronic obstructive pulmonary disease,improve or eliminate the symptoms of dyspnea,and further promote the improvement of sleep quality.