甲状腺术后并发急性下肢深静脉血栓的危险因素分析

Analysis of risk factors of acute lower extremity deep vein thrombosis after thyroid surgery

目的:探讨甲状腺术后患者并发急性下肢深静脉血栓(DVT)的临床危险因素。方法:2015年1月-2019年12月收治行甲状腺手术后出现急性下肢深静脉血栓患者17例,采用Caprini血栓风险评估表评估血栓风险,采用Logistic逐步回归分析甲状腺术后形成下肢深静脉血栓的危险因素。结果:DVT患者手术前后血浆D-二聚体及纤维蛋白原水平比较,差异有统计学意义(P<0.05);血小板水平变化情况比较,差异无统计学意义(P>0.05)。Caprini血栓风险评分≥2分是外科手术后DVT的危险因素。多因素Logistic回归分析发现,年龄>50岁、女性、恶性肿瘤为DVT的危险因素。结论:Caprini血栓风险评估为中、高危患者应及时抗凝治疗,预防血栓事件。

Objective:To explore the clinical risk factors of patients with acute lower extremity deep vein thrombosis(DVT)after thyroid surgery.Methods:From January 2015 to December 2019,17 patients with acute deep vein thrombosis of lower extremities after thyroid surgery were selected,caprini thrombosis risk assessment form was used to assess the risk of thrombosis,and Logistic stepwise regression was used to analyze the risk factors of lower extremity deep venous thrombosis after thyroid surgery.Results:The plasma D-dimer and fibrinogen levels of DVT patients before and after operation were compared,with the difference was statistically significant(P<0.05).Comparison of changes in platelet levels,with the difference was not statistically significant(P>0.05).Caprini thrombosis score≥2 is a risk factor for DVT after surgery.Multiple factors Logistic regression analysis found that age>50 years old,female,and malignant tumor were risk factors for DVT.Conclusion:The risk of thrombosis is assessed as medium and high risk patients by Caprini,which anticoagulant treatment should be timely to prevent thrombosis events.